Avigan is a mysterious drug that is not available on the market and is only used in case of emergencies.-English-

Abigan’s valuation is about to change with the corona shock. This is because the mechanism of action (i.e., how it works) indicates that it is expected to suppress the growth of the virus in the body, not only in the flu but also in the new corona.

At a special symposium of the Infectious Diseases Society of Japan, it was reported that Avigan was administered to patients infected with a new type of coronavirus, and that after 14 days of treatment, 60% of critically ill patients showed improvement in symptoms, and 90% of patients with mild or moderate illnesses showed improvement.

Dramatic recovery after Avigan administration.
A leading candidate for the world’s most promising therapeutic drug.

While no effective treatment for the new coronavirus has been found, expectations for Avigan have only grown in magazines and television programs. Now “Avigan” is being treated like a “magic potion”. But if it is such a beneficial treatment, albeit for the new strain of influenza, why isn’t it being used in the same way as the same anti-influenza drug, Tamiflu, in general circulation? Why was it strictly controlled as an emergency stockpile of medicine?

What is Fujifilm Toyama Chemical’s view of risk?

While it is understandable that emergency measures are being taken to prevent serious patients and deaths from new coronavirus infections, it is hard to know what will happen in the future if the production is rapidly expanded and the drugs are distributed around the world as they are now, without considering the risks to human health. Executives at major pharmaceutical companies also expressed their concerns.

“As far as the published data on animal testing goes, Avigan is something that a pharmaceutical company like ours would be hard-pressed to get its hands on. Even if you look at the discussions of the Pharmaceutical Affairs and Food Sanitation Council’s second subcommittee on drugs at the Ministry of Health, Labour and Welfare, Abigan has not been sufficiently confirmed to be effective against seasonal influenza, let alone highly pathogenic avian influenza. In reproductive toxicity studies, teratogenicity in humans is a concern, and in semen migration studies on adult foreign males, migration to semen has been confirmed. What’s more, the dosage is different from that used for influenza, which requires three to five times the dose for a new type of corona. It’s more of a risk. Prescriptions are accompanied by a “warning,” which is one of the biggest warnings, and can lead to serious consequences if misused. It is a last resort to be used when there is an explosion of infection and there is no other medicine to deal with it, and that is why it has been strictly controlled so that it is not distributed to the general market. I have to question the government’s policy of skipping over previous safety discussions in favor of preventing the spread of new coronaviruses.

Avigan came to the limelight when it was reported to be effective when administered to people infected with a new type of coronavirus in Wuhan, China, but the paper that claimed it was effective in China was later withdrawn. It is not our intention to sensationalize the danger, but what does Fujifilm Toyama Chemical think about the possibility of future “teratogenicity” that Avigan may cause and the risk of drug damage? When we asked the company, they replied

Avigan came to the limelight when it was reported to be effective when administered to people infected with a new type of coronavirus in Wuhan, China, but the paper that claimed it was effective in China was later withdrawn. It is not our intention to sensationalize the danger, but what does Fujifilm Toyama Chemical think about the possibility of future “teratogenicity” that Avigan may cause and the risk of drug damage? When we asked the company, they replied

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